Research ArticlePHYSIOLOGY

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

See allHide authors and affiliations

Science Advances  22 Aug 2018:
Vol. 4, no. 8, eaar8590
DOI: 10.1126/sciadv.aar8590

Article Information

vol. 4 no. 8

Online ISSN: 
History: 
  • Received for publication December 25, 2017
  • Accepted for publication July 18, 2018
  • .

Author Information

  1. Jonathan Cedernaes1,*,
  2. Milena Schönke2,,
  3. Jakub Orzechowski Westholm3,,
  4. Jia Mi4,5,
  5. Alexander Chibalin2,
  6. Sarah Voisin1,
  7. Megan Osler2,
  8. Heike Vogel6,
  9. Katarina Hörnaeus4,
  10. Suzanne L. Dickson7,
  11. Sara Bergström Lind4,
  12. Jonas Bergquist4,8,9,
  13. Helgi B Schiöth1,
  14. Juleen R. Zierath2 and
  15. Christian Benedict1
  1. 1Department of Neuroscience, Uppsala University, Uppsala, Sweden.
  2. 2Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.
  3. 3Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
  4. 4Department of Chemistry–BMC, Uppsala University, Uppsala, Sweden.
  5. 5Medicine and Pharmarcy Research Center, Binzhou Medical University, Yantai, China.
  6. 6Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Potsdam, Germany.
  7. 7Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  8. 8Department of Pathology, University of Utah, Salt Lake City, UT 84132, USA.
  9. 9Precision Medicine, Binzhou Medical University, Yantai, China.
  1. *Corresponding author. Email: jonathan.cedernaes{at}neuro.uu.se
    • These authors contributed equally to this work.

    Altmetric

    Article usage

    Article usage: August 2018 to May 2021

    AbstractFullPdf
    Aug 20184348584918
    Sep 20180246011793
    Oct 201803669493
    Nov 201801508353
    Dec 201801827295
    Jan 201971259281
    Feb 201961071232
    Mar 201961275276
    Apr 2019211146163
    May 201951033114
    Jun 201910947108
    Jul 20196113482
    Aug 201911276133
    Sep 201961281185
    Oct 201901071123
    Nov 201911288181
    Dec 20193920128
    Jan 2020269498
    Feb 20202578124
    Mar 2020283199
    Apr 20202754104
    May 20201675108
    Jun 20200591124
    Jul 2020262795
    Aug 20203709106
    Sep 20200111099
    Oct 20201623110
    Nov 20207615104
    Dec 20207662121
    Jan 20214662153
    Feb 20211579134
    Mar 20211763152
    Apr 20215661120
    May 2021229363

    Stay Connected to Science Advances

    Navigate This Article