Research ArticleSYNTHETIC BIOLOGY
BioBits™ Explorer: A modular synthetic biology education kit
- View ORCID ProfileAlly Huang1,2,3,*,
- View ORCID ProfilePeter Q. Nguyen3,4,*,
- View ORCID ProfileJessica C. Stark5,6,7,*,
- View ORCID ProfileMelissa K. Takahashi2,
- View ORCID ProfileNina Donghia3,
- Tom Ferrante3,
- View ORCID ProfileAaron J. Dy1,2,8,9,
- Karen J. Hsu10,
- View ORCID ProfileRachel S. Dubner11,
- View ORCID ProfileKeith Pardee12,
- View ORCID ProfileMichael C. Jewett5,6,7,13,14,† and
- View ORCID ProfileJames J. Collins1,2,3,8,9,15,†
- 1Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
- 2Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA.
- 3Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
- 4School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
- 5Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
- 6Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA.
- 7Center for Synthetic Biology, Northwestern University, Evanston, IL 60208, USA.
- 8Synthetic Biology Center, MIT, Cambridge, MA 02139, USA.
- 9Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
- 10Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.
- 11Department of Biological Sciences, Northwestern University, Evanston, IL 60208, USA.
- 12Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada.
- 13Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 676 North Saint Clair Street, Suite 1200, Chicago, IL 60611, USA.
- 14Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
- 15Harvard-MIT Program in Health Sciences and Technology, Cambridge, MA 02139, USA.
- ↵†Corresponding author. Email: jimjc{at}mit.edu (J.J.C.); m-jewett{at}northwestern.edu (M.C.J.)
↵* These authors contributed equally to this work.
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Science Advances 01 Aug 2018:
Vol. 4, no. 8, eaat5105
DOI: 10.1126/sciadv.aat5105
Vol. 4, no. 8, eaat5105
DOI: 10.1126/sciadv.aat5105
Ally Huang
1Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
2Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA.
3Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
Peter Q. Nguyen
3Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
4School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
Jessica C. Stark
5Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
6Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA.
7Center for Synthetic Biology, Northwestern University, Evanston, IL 60208, USA.
Melissa K. Takahashi
2Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA.
Nina Donghia
3Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
Tom Ferrante
3Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
Aaron J. Dy
1Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
2Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA.
8Synthetic Biology Center, MIT, Cambridge, MA 02139, USA.
9Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Karen J. Hsu
10Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.
Rachel S. Dubner
11Department of Biological Sciences, Northwestern University, Evanston, IL 60208, USA.
Keith Pardee
12Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada.
Michael C. Jewett
5Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
6Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA.
7Center for Synthetic Biology, Northwestern University, Evanston, IL 60208, USA.
13Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 676 North Saint Clair Street, Suite 1200, Chicago, IL 60611, USA.
14Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
James J. Collins
1Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
2Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA.
3Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
8Synthetic Biology Center, MIT, Cambridge, MA 02139, USA.
9Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
15Harvard-MIT Program in Health Sciences and Technology, Cambridge, MA 02139, USA.
