Genetic and pharmacological interventions in the aging motor nervous system slow motor aging and extend life span in C. elegans

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Science Advances  02 Jan 2019:
Vol. 5, no. 1, eaau5041
DOI: 10.1126/sciadv.aau5041

Article Information

vol. 5 no. 1

Online ISSN: 
  • Received for publication June 17, 2018
  • Accepted for publication November 26, 2018

Author Information

  1. Guang Li1,2,*,
  2. Jianke Gong1,2,*,
  3. Jie Liu2,3,
  4. Jinzhi Liu1,2,
  5. Huahua Li2,
  6. Ao-Lin Hsu4,5,6,
  7. Jianfeng Liu1, and
  8. X.Z. Shawn Xu2,4,
  1. 1International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, and College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
  2. 2Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  3. 3Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria 3800, Australia.
  4. 4Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
  5. 5Division of Geriatric and Palliative Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
  6. 6Research Center for Healthy Aging, China Medical University, Taichung 404, Taiwan.
  1. Corresponding author. Email: jfliu{at} (J.L.); shawnxu{at} (X.Z.S.X.)
  • * These authors contributed equally to this work.


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Jan 2019295182984
Feb 201952493150
Mar 201920388130
Apr 20193030684
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Jun 20191226439
Jul 20191010139

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