Research ArticleIMMUNOLOGY

VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1β in macrophages

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Science Advances  09 Jan 2019:
Vol. 5, no. 1, eaau7426
DOI: 10.1126/sciadv.aau7426

Article Information

vol. 5 no. 1

Online ISSN: 
History: 
  • Received for publication July 11, 2018
  • Accepted for publication November 30, 2018

Author Information

  1. Xiaoyong Huang1,*,
  2. Zeqing Feng1,*,
  3. Yuanzhong Jiang2,
  4. Jialin Li1,
  5. Qun Xiang1,
  6. Sheng Guo1,
  7. Chengying Yang1,
  8. Lei Fei1,
  9. Guoning Guo3,
  10. Lixin Zheng4,
  11. Yuzhang Wu1, and
  12. Yongwen Chen1,
  1. 1Institute of Immunology, PLA, Third Military Medical University, Chongqing 400038, People’s Republic of China.
  2. 2MOE Key Laboratory for Bio-resources and Eco-environment, College of Life Science, Sichuan University, Chengdu 610064, People’s Republic of China.
  3. 3Department of Emergency, Southwest Hospital, Third Military Medical University, Chongqing 400038, People's Republic of China.
  4. 4Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MA, USA.
  1. Corresponding author. Email: chenyongwen{at}tmmu.edu.cn (Y.C.); wuyuzhang{at}tmmu.edu.cn (Y.W.)
  • * These authors contributed equally to this work.

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