Research ArticleNEUROSCIENCE

Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection

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Science Advances  09 Jan 2019:
Vol. 5, no. 1, eaau9940
DOI: 10.1126/sciadv.aau9940

Article Information

vol. 5 no. 1

Online ISSN: 
History: 
  • Received for publication August 3, 2018
  • Accepted for publication November 28, 2018

Author Information

  1. Alejandra Daruich1,2,3,
  2. Quentin Le Rouzic1,
  3. Laurent Jonet1,
  4. Marie-Christine Naud1,
  5. Laura Kowalczuk2,
  6. Jean-Antoine Pournaras2,
  7. Jeffrey H. Boatright4,5,
  8. Aurélien Thomas6,7,
  9. Natacha Turck7,8,
  10. Alexandre Moulin2,
  11. Francine Behar-Cohen1,7,9,*, and
  12. Emilie Picard1,*
  1. 1INSERM, UMRS1138, Team 17, From physiopathology of ocular diseases to clinical development, Université Sorbonne Paris Cité, Centre de Recherche des Cordeliers, 15 rue de l’Ecole de Médecine, 75006 Paris, France.
  2. 2Department of ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland.
  3. 3Ophthalmology Department, Necker-Enfants Malades University Hospital, AP-HP, Paris, France.
  4. 4Department of Ophthalmology, School of Medicine, Emory University, Atlanta, GA, USA.
  5. 5Center of Excellence, Atlanta Veterans Administration Medical Center, Decatur, GA, USA.
  6. 6Geneva University Hospitals, Unit of Toxicology, CURML, Geneva, Switzerland.
  7. 7Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 21, 1011 Lausanne, Switzerland.
  8. 8Geneva University, Department of Human Protein Science, Geneva, Switzerland.
  9. 9Ophtalmopole, Cochin Hospital, AP-HP, Assistance Publique Hôpitaux de Paris, 24 rue du Faubourg Saint-Jacques, 75014 Paris, France.
  1. Corresponding author. Email: francine.behar{at}gmail.com
  • * These authors contributed equally to this work.

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