Research ArticleIMMUNOLOGY
Red blood cell–derived nanoerythrosome for antigen delivery with enhanced cancer immunotherapy
- View ORCID ProfileXiao Han1,*,
- View ORCID ProfileShufang Shen1,*,
- Qin Fan1,
- Guojun Chen2,
- Edikan Archibong3,
- Gianpietro Dotti3,
- Zhuang Liu1,†,
- View ORCID ProfileZhen Gu2,4,† and
- View ORCID ProfileChao Wang1,†
- 1Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu 215123, China.
- 2Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
- 3Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
- 4California NanoSystems Institute, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA.
- ↵†Corresponding author. Email: cwang{at}suda.edu.cn (C.W.); guzhen{at}ucla.edu (Z.G.); zliu{at}suda.edu.cn (Z.L.)
↵* These authors contributed equally to this work.
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Science Advances 23 Oct 2019:
Vol. 5, no. 10, eaaw6870
DOI: 10.1126/sciadv.aaw6870
Vol. 5, no. 10, eaaw6870
DOI: 10.1126/sciadv.aaw6870
Xiao Han
1Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu 215123, China.
Shufang Shen
1Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu 215123, China.
Qin Fan
1Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu 215123, China.
Guojun Chen
2Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Edikan Archibong
3Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Gianpietro Dotti
3Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Zhuang Liu
1Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu 215123, China.
Zhen Gu
2Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
4California NanoSystems Institute, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Chao Wang
1Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu 215123, China.