Research ArticleVIROLOGY

HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly

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Science Advances  02 Oct 2019:
Vol. 5, no. 10, eaaw8651
DOI: 10.1126/sciadv.aaw8651

Article Information

vol. 5 no. 10

Online ISSN: 
History: 
  • Received for publication January 31, 2019
  • Accepted for publication September 9, 2019
  • .

Author Information

  1. C. Favard1,*,
  2. J. Chojnacki2,3,*,
  3. P. Merida1,
  4. N. Yandrapalli1,
  5. J. Mak4,
  6. C. Eggeling2,5,6, and
  7. D. Muriaux1,
  1. 1Montpellier Infectious Disease Research Institute, IRIM, CNRS–Université Montpellier, 1919, route de Mende, 34293 Montpellier Cedex, France.
  2. 2MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
  3. 3IrsiCaixa AIDS Research Institute, University Hospital Germans Trias i Pujol, Ctra. de Canyet s/n, Badalona, 08916 Barcelona, Spain.
  4. 4Institute for Glycomics, Griffith University Gold Coast, Southport, QLD, Australia.
  5. 5Institute of Applied Optics and Biophysics, Friedrich-Schiller-University Jena, Max-Wien Platz 4, 07743 Jena, Germany.
  6. 6Leibniz Institute of Photonic Technology e.V., Albert-Einstein-Straße 9, 07745 Jena, Germany.
  1. Corresponding author. Email: delphine.muriaux{at}irim.cnrs.fr (D.M.); christian.eggeling{at}rdm.ox.ac.uk (C.E.)
  • * These authors contributed equally to this work.

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