Research ArticleSTRUCTURAL BIOLOGY

Cryo–electron microscopy structure and analysis of the P-Rex1–Gβγ signaling scaffold

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Science Advances  16 Oct 2019:
Vol. 5, no. 10, eaax8855
DOI: 10.1126/sciadv.aax8855

Article Information

vol. 5 no. 10

Online ISSN: 
History: 
  • Received for publication May 1, 2019
  • Accepted for publication September 22, 2019
  • .

Author Information

  1. Jennifer N. Cash1,
  2. Sarah Urata2,
  3. Sheng Li2,
  4. Sandeep K. Ravala3,
  5. Larisa V. Avramova3,
  6. Michael D. Shost1,
  7. J. Silvio Gutkind4,
  8. John J. G. Tesmer3,* and
  9. Michael A. Cianfrocco1,*
  1. 1Department of Biological Chemistry & Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
  2. 2Department of Medicine, University of California, San Diego, San Diego, CA, USA.
  3. 3Departments of Biological Sciences and of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.
  4. 4Department of Pharmacology and Moores Cancer Center, University of California, San Diego, San Diego, CA, USA.
  1. *Corresponding author. Email: jtesmer{at}purdue.edu (J.J.G.T.); mcianfro{at}umich.edu (M.A.C.)

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