Research ArticleMOLECULAR BIOLOGY

LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells

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Science Advances  02 Oct 2019:
Vol. 5, no. 10, eaay3068
DOI: 10.1126/sciadv.aay3068

Article Information

vol. 5 no. 10

Online ISSN: 
History: 
  • Received for publication June 6, 2019
  • Accepted for publication September 5, 2019
  • .

Author Information

  1. Gary LeRoy1,2,*,
  2. Ozgur Oksuz1,2,*,
  3. Nicolas Descostes1,2,3,*,
  4. Yuki Aoi4,
  5. Rais A. Ganai1,2,
  6. Havva Ortabozkoyun Kara1,2,
  7. Jia-Ray Yu1,2,
  8. Chul-Hwan Lee1,2,
  9. James Stafford1,2,
  10. Ali Shilatifard4 and
  11. Danny Reinberg1,2,
  1. 1Howard Hughes Medical Institute, New York University School of Medicine, New York, NY 10016, USA.
  2. 2Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
  3. 3EMBL Rome, Adriano Buzzati-Traverso Campus, Via Ramarini 32, 00015 Monterotondo (RM), Italy.
  4. 4Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  1. Corresponding author. Email: danny.reinberg{at}nyumc.org
  • * These authors contributed equally to this work.

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