Rational discovery of antimetastatic agents targeting the intrinsically disordered region of MBD2

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Science Advances  20 Nov 2019:
Vol. 5, no. 11, eaav9810
DOI: 10.1126/sciadv.aav9810

Article Information

vol. 5 no. 11

Online ISSN: 
  • Received for publication November 7, 2018
  • Accepted for publication September 20, 2019
  • .

Author Information

  1. Min Young Kim1,*,
  2. Insung Na2,*,,
  3. Ji Sook Kim1,3,
  4. Seung Han Son1,
  5. Sungwoo Choi1,
  6. Seol Eui Lee1,
  7. Ji-Hun Kim4,
  8. Kiseok Jang3,
  9. Gil Alterovitz5,
  10. Yu Chen2,
  11. Arjan van der Vaart6,
  12. Hyung-Sik Won7,,
  13. Vladimir N. Uversky2,8, and
  14. Chul Geun Kim1,
  1. 1Department of Life Science and Research Institute for Natural Sciences, Hanyang University, Seoul 04763, Korea.
  2. 2Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.
  3. 3Department of Pathology, Hanyang University College of Medicine, Seoul 04763, Korea.
  4. 4College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28160, Korea.
  5. 5Boston Children's Hospital/Harvard Medical School, Boston, MA 02115, USA.
  6. 6Department of Chemistry, University of South Florida, Tampa, FL 33620, USA.
  7. 7Department of Biotechnology, Konkuk University, Chungju, Chungbuk 27478, Korea.
  8. 8Institute for Biological Instrumentation of the Russian Academy of Sciences, Pushchino, Moscow Region 142290, Russia.
  1. Corresponding author. Email: cgkim{at} (C.G.K.); wonhs{at} (H.-S.W.); vuversky{at} (V.N.U.)
  • * These authors contributed equally to this work.

  • Present address: Boston Children’s Hospital/Harvard Medical School, Boston, MA 02115, USA.


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