Research ArticleCELL BIOLOGY

Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy

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Science Advances  27 Nov 2019:
Vol. 5, no. 11, eaav9879
DOI: 10.1126/sciadv.aav9879

Article Information

vol. 5 no. 11

Online ISSN: 
History: 
  • Received for publication November 7, 2018
  • Accepted for publication September 17, 2019
  • .

Author Information

  1. C. Flores1,*,
  2. T. Wildes1,,
  3. B. DiVita Dean1,,
  4. G. Moore1,
  5. J. Drake1,
  6. R. Abraham1,
  7. J. Gil1,
  8. O. Yegorov1,
  9. C. Yang1,
  10. J. Dean1,
  11. C. Moneypenny1,
  12. D. Shin1,2,
  13. C. Pham1,
  14. J. Krauser1,
  15. J. King1,
  16. G. Grant3,
  17. T. Driscoll4,
  18. J. Kurtzberg4,
  19. R. McLendon5,
  20. S. Gururangan1,6 and
  21. D. Mitchell1,*
  1. 1University of Florida Brain Tumor Immunotherapy Program, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Lillian S. Wells Department of Neurosurgery, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.
  2. 2U.S. Army, 1600 Spearhead Division Ave., Fort Knox, KY, USA.
  3. 3Department of Neurosurgery, Stanford University Medical Center, Palo Alto, CA, USA.
  4. 4Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.
  5. 5Department of Pathology, Duke University Medical Center, Durham, NC, USA.
  6. 6Department of Pediatrics, University of Florida, Gainesville, FL, USA.
  1. *Corresponding author. Email: catherine.flores{at}neurosurgery.ufl.edu (C.F.); duane.mitchell{at}neurosurgery.ufl.edu (D.M.)
  • These authors contributed equally to this work.

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