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Research ArticleCELL BIOLOGY
In vivo–mimicking microfluidic perfusion culture of pancreatic islet spheroids
- View ORCID ProfileYesl Jun1,2,
- View ORCID ProfileJaeSeo Lee3,
- View ORCID ProfileSeongkyun Choi2,
- View ORCID ProfileJi Hun Yang2,4,
- Maike Sander1,*,
- View ORCID ProfileSeok Chung2,3,* and
- Sang-Hoon Lee3,5
- 1Departments of Pediatrics and Cellular and Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA.
- 2School of Mechanical Engineering, Korea University, Seoul 02841, Republic of Korea.
- 3KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea.
- 4Next & Bio Inc., Seoul National University, Seoul 08826, Republic of Korea.
- 5School of Biomedical Engineering, Korea University, Seoul 02841, Republic of Korea.
- ↵*Corresponding author. Email: sidchung{at}korea.ac.kr (S.C.); masander{at}ucsd.edu (M.S.)
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Science Advances 27 Nov 2019:
Vol. 5, no. 11, eaax4520
DOI: 10.1126/sciadv.aax4520
Vol. 5, no. 11, eaax4520
DOI: 10.1126/sciadv.aax4520
Yesl Jun
1Departments of Pediatrics and Cellular and Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA.
2School of Mechanical Engineering, Korea University, Seoul 02841, Republic of Korea.
JaeSeo Lee
3KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea.
Seongkyun Choi
2School of Mechanical Engineering, Korea University, Seoul 02841, Republic of Korea.
Ji Hun Yang
2School of Mechanical Engineering, Korea University, Seoul 02841, Republic of Korea.
4Next & Bio Inc., Seoul National University, Seoul 08826, Republic of Korea.
Maike Sander
1Departments of Pediatrics and Cellular and Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA.
Seok Chung
2School of Mechanical Engineering, Korea University, Seoul 02841, Republic of Korea.
3KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea.
Sang-Hoon Lee
3KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea.
5School of Biomedical Engineering, Korea University, Seoul 02841, Republic of Korea.
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