Research ArticleHEALTH AND MEDICINE

Brain-targeted enzyme-loaded nanoparticles: A breach through the blood-brain barrier for enzyme replacement therapy in Krabbe disease

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Science Advances  20 Nov 2019:
Vol. 5, no. 11, eaax7462
DOI: 10.1126/sciadv.aax7462

Article Information

vol. 5 no. 11

Online ISSN: 
History: 
  • Received for publication April 18, 2019
  • Accepted for publication September 19, 2019
  • .

Author Information

  1. Ambra Del Grosso1,*,
  2. Marianna Galliani1,2,*,
  3. Lucia Angella1,
  4. Melissa Santi2,
  5. Ilaria Tonazzini1,
  6. Gabriele Parlanti1,
  7. Giovanni Signore1,3, and
  8. Marco Cecchini1,
  1. 1NEST, Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, Italy.
  2. 2Center for Nanotechnology Innovation@NEST, Piazza San Silvestro 12, 56127 Pisa, Italy.
  3. 3Fondazione Pisana per la Scienza ONLUS, 56017 Pisa, Italy.
  1. Corresponding author. Email: marco.cecchini{at}nano.cnr.it (M.C.); g.signore{at}fpscience.it (G.S.)
  • * These authors contributed equally to this work.

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