Research ArticleGENETICS

SpCas9 activity prediction by DeepSpCas9, a deep learning–based model with high generalization performance

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Science Advances  06 Nov 2019:
Vol. 5, no. 11, eaax9249
DOI: 10.1126/sciadv.aax9249

Article Information

vol. 5 no. 11

Online ISSN: 
History: 
  • Received for publication May 6, 2019
  • Accepted for publication September 16, 2019
  • .

Author Information

  1. Hui Kwon Kim1,2,*,
  2. Younggwang Kim1,2,*,
  3. Sungtae Lee1,
  4. Seonwoo Min3,
  5. Jung Yoon Bae1,
  6. Jae Woo Choi1,4,
  7. Jinman Park1,2,
  8. Dongmin Jung1,4,
  9. Sungroh Yoon3,5 and
  10. Hyongbum Henry Kim1,2,4,6,7,
  1. 1Department of Pharmacology, Yonsei University College of Medicine, Seoul, Republic of Korea.
  2. 2Brain Korea 21 Plus Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea.
  3. 3Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea.
  4. 4Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
  5. 5Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Republic of Korea.
  6. 6Center for Nanomedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea.
  7. 7Yonsei-IBS Institute, Yonsei University, Seoul, Republic of Korea.
  1. Corresponding author. Email: hkim1{at}yuhs.ac
  • * These authors contributed equally to this work.

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