Research ArticleMOLECULAR BIOLOGY
SCAN1-TDP1 trapping on mitochondrial DNA promotes mitochondrial dysfunction and mitophagy
- View ORCID ProfileArijit Ghosh1,
- Sangheeta Bhattacharjee1,
- Srijita Paul Chowdhuri1,
- Abhik Mallick2,
- Ishita Rehman1,
- Sudipta Basu3 and
- View ORCID ProfileBenu Brata Das1,*
- 1Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
- 2Department of Chemistry, Indian Institute of Science Education and Research (IISER) Pune, Dr. Homi Bhabha Road, Pashan, Pune, Maharashtra 411008, India.
- 3Discipline of Chemistry, Indian Institute of Technology (IIT) Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India.
- ↵*Corresponding author. Email: pcbbd{at}iacs.res.in
See allHide authors and affiliations
Science Advances 06 Nov 2019:
Vol. 5, no. 11, eaax9778
DOI: 10.1126/sciadv.aax9778
Vol. 5, no. 11, eaax9778
DOI: 10.1126/sciadv.aax9778
Arijit Ghosh
1Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
Sangheeta Bhattacharjee
1Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
Srijita Paul Chowdhuri
1Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
Abhik Mallick
2Department of Chemistry, Indian Institute of Science Education and Research (IISER) Pune, Dr. Homi Bhabha Road, Pashan, Pune, Maharashtra 411008, India.
Ishita Rehman
1Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
Sudipta Basu
3Discipline of Chemistry, Indian Institute of Technology (IIT) Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India.
Benu Brata Das
1Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.