Research ArticleCELL BIOLOGY

Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

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Science Advances  11 Dec 2019:
Vol. 5, no. 12, eaaw3413
DOI: 10.1126/sciadv.aaw3413

Article Information

vol. 5 no. 12

Online ISSN: 
History: 
  • Received for publication December 11, 2018
  • Accepted for publication October 15, 2019
  • .

Author Information

  1. Grant E. Duclos1,*,
  2. Vitor H. Teixeira2,
  3. Patrick Autissier3,
  4. Yaron B. Gesthalter4,
  5. Marjan A. Reinders-Luinge5,
  6. Robert Terrano1,
  7. Yves M. Dumas1,
  8. Gang Liu1,
  9. Sarah A. Mazzilli1,
  10. Corry-Anke Brandsma5,
  11. Maarten van den Berge6,
  12. Sam M. Janes2,7,
  13. Wim Timens5,
  14. Marc E. Lenburg1,
  15. Avrum Spira1,8,
  16. Joshua D. Campbell1,*, and
  17. Jennifer Beane1,*,
  1. 1Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  2. 2Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.
  3. 3Boston University Flow Cytometry Core Facility, Boston University School of Medicine, Boston, MA, USA.
  4. 4Department of Medicine, University of California San Francisco School of Medicine, San Francisco, CA, USA.
  5. 5University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, Netherlands.
  6. 6University of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, Netherlands.
  7. 7Department of Thoracic Medicine, University College London Hospital, London, UK.
  8. 8Johnson & Johnson Innovation, Cambridge, MA, USA.
  1. *Corresponding author. Email: duclosgr{at}bu.edu (G.E.D.); camp{at}bu.edu (J.D.C.); jbeane{at}bu.edu (J.B.)
  • These authors contributed equally to this work.

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