Research ArticleCANCER
Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy
- John-Michael Williford1,*,
- Jun Ishihara1,*,
- Ako Ishihara1,
- Aslan Mansurov1,
- Peyman Hosseinchi1,
- Tiffany M. Marchell1,2,
- Lambert Potin1,3,
- Melody A. Swartz1,2,4 and
- Jeffrey A. Hubbell1,2,†
- 1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
- 2Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.
- 3Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
- 4Ben May Department for Cancer Research, University of Chicago, Chicago, IL 60637, USA.
- ↵†Corresponding author. Email: jhubbell{at}uchicago.edu
↵* These authors contributed equally to this work.
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Science Advances 11 Dec 2019:
Vol. 5, no. 12, eaay1357
DOI: 10.1126/sciadv.aay1357
Vol. 5, no. 12, eaay1357
DOI: 10.1126/sciadv.aay1357
John-Michael Williford
1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
Jun Ishihara
1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
Ako Ishihara
1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
Aslan Mansurov
1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
Peyman Hosseinchi
1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
Tiffany M. Marchell
1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
2Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.
Lambert Potin
1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
3Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Melody A. Swartz
1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
2Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.
4Ben May Department for Cancer Research, University of Chicago, Chicago, IL 60637, USA.
Jeffrey A. Hubbell
1Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.
2Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.
