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Research ArticleMICROBIOLOGY
Influenza binds phosphorylated glycans from human lung
- Lauren Byrd-Leotis1,2,*,
- Nan Jia2,*,
- Sucharita Dutta2,
- Jessica F. Trost1,
- Chao Gao2,
- Sandra F. Cummings2,
- Thomas Braulke3,
- Sven Müller-Loennies4,
- Jamie Heimburg-Molinaro2,
- David A. Steinhauer1,† and
- Richard D. Cummings2,†
- 1Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
- 2Beth Israel Deaconess Medical Center, Department of Surgery and Harvard Medical School Center for Glycoscience, Harvard Medical School, Boston, MA, USA.
- 3Department of Biochemistry, Children’s Hospital, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
- 4Research Center Borstel (RCB), Leibniz Lung Center, Division Biophysics, Parkallee 22, D-23845 Borstel, Germany.
- ↵†Corresponding author. Email: dsteinh{at}emory.edu (D.A.S.); rcummin1{at}bidmc.harvard.edu (R.D.C.)
↵* These authors contributed equally to this work as co-first authors.
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Science Advances 13 Feb 2019:
Vol. 5, no. 2, eaav2554
DOI: 10.1126/sciadv.aav2554
Vol. 5, no. 2, eaav2554
DOI: 10.1126/sciadv.aav2554
Lauren Byrd-Leotis
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.Beth Israel Deaconess Medical Center, Department of Surgery and Harvard Medical School Center for Glycoscience, Harvard Medical School, Boston, MA, USA.
Nan Jia
Beth Israel Deaconess Medical Center, Department of Surgery and Harvard Medical School Center for Glycoscience, Harvard Medical School, Boston, MA, USA.
Sucharita Dutta
Beth Israel Deaconess Medical Center, Department of Surgery and Harvard Medical School Center for Glycoscience, Harvard Medical School, Boston, MA, USA.
Jessica F. Trost
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Chao Gao
Beth Israel Deaconess Medical Center, Department of Surgery and Harvard Medical School Center for Glycoscience, Harvard Medical School, Boston, MA, USA.
Sandra F. Cummings
Beth Israel Deaconess Medical Center, Department of Surgery and Harvard Medical School Center for Glycoscience, Harvard Medical School, Boston, MA, USA.
Thomas Braulke
Department of Biochemistry, Children’s Hospital, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.
Sven Müller-Loennies
Research Center Borstel (RCB), Leibniz Lung Center, Division Biophysics, Parkallee 22, D-23845 Borstel, Germany.
Jamie Heimburg-Molinaro
Beth Israel Deaconess Medical Center, Department of Surgery and Harvard Medical School Center for Glycoscience, Harvard Medical School, Boston, MA, USA.
David A. Steinhauer
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Richard D. Cummings
Beth Israel Deaconess Medical Center, Department of Surgery and Harvard Medical School Center for Glycoscience, Harvard Medical School, Boston, MA, USA.
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