Research ArticleCELL BIOLOGY

Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells

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Science Advances  13 Mar 2019:
Vol. 5, no. 3, eaau7887
DOI: 10.1126/sciadv.aau7887

Article Information

vol. 5 no. 3

Online ISSN: 
History: 
  • Received for publication July 16, 2018
  • Accepted for publication January 30, 2019

Author Information

  1. Xiangxiang Wei1,*,
  2. Jieyu Guo1,*,
  3. Qinhan Li1,
  4. Qianqian Jia2,
  5. Qing Jing2,
  6. Yan Li3,
  7. Bin Zhou3,
  8. Jiayu Chen4,
  9. Shaorong Gao4,
  10. Xinyue Zhang1,
  11. Mengping Jia1,
  12. Cong Niu1,
  13. Wenlong Yang5,
  14. Xiuling Zhi1,
  15. Xinhong Wang1,
  16. Dian Yu1,
  17. Lufeng Bai6,
  18. Lin Wang6,
  19. Jie Na6,
  20. Yunzeng Zou5,
  21. Jianyi Zhang7,
  22. Shuning Zhang5, and
  23. Dan Meng1,
  1. 1Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  2. 2CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
  3. 3The State Key Laboratory of Cell Biology, CAS Center for Excellence on Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
  4. 4Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
  5. 5Department of Cardiology, Zhongshan Hospital, Shanghai Cardiovascular Medical Center, Shanghai Institute of Cardiovascular Diseases, Institute of Pan-vascular Medicine, Fudan University, Shanghai 200032, China.
  6. 6Center for Stem Cell Biology and Regenerative Medicine, School of Medicine, Tsinghua University, Beijing 100084, China.
  7. 7Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  1. Corresponding author. Email: dmeng{at}fudan.edu.cn (D.M.); zhang.shuning{at}zs-hospital.sh.cn (S.Z.)
  • * These authors contributed equally to this work.

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