Research ArticleIMMUNOLOGY
Immunomodulatory nanogels overcome restricted immunity in a murine model of gut microbiome–mediated metabolic syndrome
- Matthew J. Mosquera1,2,
- Sungwoong Kim3,
- Hao Zhou4,
- Tina T. Jing1,
- Marysol Luna2,
- Jason D. Guss1,
- Pooja Reddy5,
- Kristine Lai1,2,
- Cynthia A. Leifer6,
- Ilana L. Brito1,
- Christopher J. Hernandez1,2 and
- Ankur Singh1,2,7,*
- 1Meinig School of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
- 2Sibley School of Mechanical and Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
- 3Department of Materials Science and Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
- 4Department of Microbiology, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA.
- 5Biological Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA.
- 6Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
- 7Englander Institute for Precision Medicine, Weill Cornell Medical College of Cornell University, New York, NY 10021, USA.
- ↵*Corresponding author. Email: as2833{at}cornell.edu
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Science Advances 27 Mar 2019:
Vol. 5, no. 3, eaav9788
DOI: 10.1126/sciadv.aav9788
Vol. 5, no. 3, eaav9788
DOI: 10.1126/sciadv.aav9788
Matthew J. Mosquera
Meinig School of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.Sibley School of Mechanical and Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
Sungwoong Kim
Department of Materials Science and Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
Hao Zhou
Department of Microbiology, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA.
Tina T. Jing
Meinig School of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
Marysol Luna
Sibley School of Mechanical and Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
Jason D. Guss
Meinig School of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
Pooja Reddy
Biological Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA.
Kristine Lai
Meinig School of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.Sibley School of Mechanical and Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
Cynthia A. Leifer
Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
Ilana L. Brito
Meinig School of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
Christopher J. Hernandez
Meinig School of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.Sibley School of Mechanical and Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
Ankur Singh
Meinig School of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.Sibley School of Mechanical and Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.Englander Institute for Precision Medicine, Weill Cornell Medical College of Cornell University, New York, NY 10021, USA.
