Structure and mechanisms of sodium-pumping KR2 rhodopsin

Kirill Kovalev; Vitaly Polovinkin; Ivan Gushchin; Alexey Alekseev; Vitaly Shevchenko; Valentin Borshchevskiy; Roman Astashkin; Taras Balandin; Dmitry Bratanov; Svetlana Vaganova; Alexander Popov; Vladimir Chupin; Georg Büldt; Ernst Bamberg; Valentin Gordeliy

doi:10.1126/sciadv.aav2671

Research ArticleMOLECULAR BIOLOGY

Structure and mechanisms of sodium-pumping KR2 rhodopsin

View ORCID ProfileKirill Kovalev¹,²,³,⁴,*,
View ORCID ProfileVitaly Polovinkin¹,²,*,
View ORCID ProfileIvan Gushchin³,
View ORCID ProfileAlexey Alekseev²,³,⁴,
View ORCID ProfileVitaly Shevchenko²,³,⁴,
View ORCID ProfileValentin Borshchevskiy³,
View ORCID ProfileRoman Astashkin¹,³,
View ORCID ProfileTaras Balandin²,
Dmitry Bratanov¹,²,
Svetlana Vaganova²,
View ORCID ProfileAlexander Popov⁵,
Vladimir Chupin³,
Georg Büldt³,
View ORCID ProfileErnst Bamberg³,⁶,† and
View ORCID ProfileValentin Gordeliy¹,²,³,†

¹Institut de Biologie Structurale, Université Grenoble Alpes-CEA-CNRS, Grenoble, France.
²Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.
³Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.
⁴Institute of Crystallography, University of Aachen (RWTH), Aachen, Germany.
⁵European Synchrotron Radiation Facility, 38043 Grenoble, France.
⁶Max Planck Institute of Biophysics, Frankfurt am Main, Germany.

↵†Corresponding author. Email: valentin.gordeliy{at}ibs.fr (V.G.); ernst.bamberg{at}biophys.mpg.de (E.B.)

↵* These authors contributed equally to this work.

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Science Advances 10 Apr 2019:
Vol. 5, no. 4, eaav2671
DOI: 10.1126/sciadv.aav2671

Kirill Kovalev

1Institut de Biologie Structurale, Université Grenoble Alpes-CEA-CNRS, Grenoble, France.

2Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

4Institute of Crystallography, University of Aachen (RWTH), Aachen, Germany.

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Vitaly Polovinkin

1Institut de Biologie Structurale, Université Grenoble Alpes-CEA-CNRS, Grenoble, France.

2Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.

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Ivan Gushchin

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

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Alexey Alekseev

2Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

4Institute of Crystallography, University of Aachen (RWTH), Aachen, Germany.

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Vitaly Shevchenko

2Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

4Institute of Crystallography, University of Aachen (RWTH), Aachen, Germany.

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Valentin Borshchevskiy

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

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Roman Astashkin

1Institut de Biologie Structurale, Université Grenoble Alpes-CEA-CNRS, Grenoble, France.

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

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Taras Balandin

2Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.

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Dmitry Bratanov

1Institut de Biologie Structurale, Université Grenoble Alpes-CEA-CNRS, Grenoble, France.

2Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.

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Svetlana Vaganova

2Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.

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Alexander Popov

5European Synchrotron Radiation Facility, 38043 Grenoble, France.

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Vladimir Chupin

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

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Georg Büldt

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

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Ernst Bamberg

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

6Max Planck Institute of Biophysics, Frankfurt am Main, Germany.

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For correspondence: valentin.gordeliy@ibs.fr ernst.bamberg@biophys.mpg.de

Valentin Gordeliy

1Institut de Biologie Structurale, Université Grenoble Alpes-CEA-CNRS, Grenoble, France.

2Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Centre Juelich, Juelich, Germany.

3Moscow Institute of Physics and Technology, Dolgoprudniy, Russia.

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ORCID record for Valentin Gordeliy
For correspondence: valentin.gordeliy@ibs.fr ernst.bamberg@biophys.mpg.de

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