Research ArticleEVOLUTIONARY BIOLOGY
Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction
- Jacqueline A. Robinson1,*,†,
- Jannikke Räikkönen2,
- Leah M. Vucetich3,
- John A. Vucetich3,
- Rolf O. Peterson3,
- Kirk E. Lohmueller1,4,5,‡ and
- Robert K. Wayne1,‡
- 1Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA.
- 2Department of Environmental Research and Monitoring, Swedish Museum of Natural History, Box 50007, 10405 Stockholm, Sweden.
- 3School of Forest Resources and Environmental Science, Michigan Technological University, Houghton, MI 49931, USA.
- 4Interdepartmental Program in Bioinformatics, University of California, Los Angeles, CA 90095, USA.
- 5Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
- ↵*Corresponding author. Email: jacqueline.robinson{at}ucsf.edu
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Science Advances 29 May 2019:
Vol. 5, no. 5, eaau0757
DOI: 10.1126/sciadv.aau0757
Vol. 5, no. 5, eaau0757
DOI: 10.1126/sciadv.aau0757
Jacqueline A. Robinson
1Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA.
Jannikke Räikkönen
2Department of Environmental Research and Monitoring, Swedish Museum of Natural History, Box 50007, 10405 Stockholm, Sweden.
Leah M. Vucetich
3School of Forest Resources and Environmental Science, Michigan Technological University, Houghton, MI 49931, USA.
John A. Vucetich
3School of Forest Resources and Environmental Science, Michigan Technological University, Houghton, MI 49931, USA.
Rolf O. Peterson
3School of Forest Resources and Environmental Science, Michigan Technological University, Houghton, MI 49931, USA.
Kirk E. Lohmueller
1Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA.
4Interdepartmental Program in Bioinformatics, University of California, Los Angeles, CA 90095, USA.
5Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Robert K. Wayne
1Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA.
