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Molecular insights into the surface-catalyzed secondary nucleation of amyloid-β40 (Aβ40) by the peptide fragment Aβ16–22

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Science Advances  21 Jun 2019:
Vol. 5, no. 6, eaav8216
DOI: 10.1126/sciadv.aav8216

Article Information

vol. 5 no. 6

Online ISSN: 
History: 
  • Received for publication October 24, 2018
  • Accepted for publication May 15, 2019
  • .

Author Information

  1. Samuel J. Bunce1,2,*,
  2. Yiming Wang3,*,
  3. Katie L. Stewart2,4,
  4. Alison E. Ashcroft2,4,
  5. Sheena E. Radford2,4,,
  6. Carol K. Hall3, and
  7. Andrew J. Wilson1,2,
  1. 1School of Chemistry, University of Leeds, Leeds LS2 9JT, UK.
  2. 2Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
  3. 3Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905, USA.
  4. 4School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
  1. Corresponding author. Email: s.e.radford{at}leeds.ac.uk (S.E.R.); hall{at}ncsu.edu (C.K.H.); a.j.wilson{at}leeds.ac.uk (A.J.W.)
  • * These authors contributed equally to this work.

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