Research ArticleCELL BIOLOGY

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

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Science Advances  05 Jun 2019:
Vol. 5, no. 6, eaaw0254
DOI: 10.1126/sciadv.aaw0254

Article Information

vol. 5 no. 6

Online ISSN: 
History: 
  • Received for publication November 11, 2018
  • Accepted for publication April 26, 2019
  • .

Author Information

  1. Priya Hari1,
  2. Fraser R. Millar1,
  3. Nuria Tarrats1,
  4. Jodie Birch2,
  5. Andrea Quintanilla1,
  6. Curtis J. Rink3,4,
  7. Irene Fernández-Duran1,
  8. Morwenna Muir1,
  9. Andrew J. Finch1,
  10. Valerie G. Brunton1,
  11. João F. Passos2,5,
  12. Jennifer P. Morton3,4,
  13. Luke Boulter6 and
  14. Juan Carlos Acosta1,*
  1. 1Cancer Research UK Edinburgh Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.
  2. 2Institute for Cell and Molecular Biosciences, Campus for Ageing and Vitality, Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
  3. 3Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  4. 4Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
  5. 5Department of Physiology and Biochemical Engineering Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
  6. 6MRC-Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.
  1. *Corresponding author. Email: juan-carlos.acosta{at}igmm.ed.ac.uk

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