Research ArticleGENETICS

Genomic determinants of speciation and spread of the Mycobacterium tuberculosis complex

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Science Advances  12 Jun 2019:
Vol. 5, no. 6, eaaw3307
DOI: 10.1126/sciadv.aaw3307

Article Information

vol. 5 no. 6

Online ISSN: 
  • Received for publication December 10, 2018
  • Accepted for publication May 10, 2019
  • .

Author Information

  1. Á. Chiner-Oms1,*,
  2. L. Sánchez-Busó2,*,
  3. J. Corander2,3,4,
  4. S. Gagneux5,6,
  5. S. R. Harris7,
  6. D. Young8,
  7. F. González-Candelas1,9 and
  8. I. Comas9,10,
  1. 1Unidad Mixta “Infección y Salud Pública” FISABIO-CSISP/Universidad de Valencia, Instituto de Biología Integrativa de Sistemas (I2SysBio), Valencia, Spain.
  2. 2Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.
  3. 3Department of Biostatistics, University of Oslo, 0317 Oslo, Norway.
  4. 4Helsinki Institute of Information Technology (HIIT), Department of Mathematics and Statistics, University of Helsinki, 00014 Helsinki, Finland.
  5. 5Swiss Tropical and Public Health Institute, Basel, Switzerland.
  6. 6University of Basel, Basel, Switzerland.
  7. 7Microbiotica, BioData Innovation Centre, Wellcome Genome Campus, Cambridge CB10 1DR, UK.
  8. 8The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  9. 9CIBER en Epidemiología y Salud Pública, Valencia, Spain.
  10. 10Instituto de Biomedicina de Valencia (IBV-CSIC), Valencia, Spain.
  1. Corresponding author. Email: icomas{at}
  • * These authors contributed equally to this work.


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Jul 2019321071170
Aug 201910392120
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