Research ArticleSYNTHETIC BIOLOGY

High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA

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Science Advances  05 Jun 2019:
Vol. 5, no. 6, eaaw9180
DOI: 10.1126/sciadv.aaw9180

Article Information

vol. 5 no. 6

Online ISSN: 
History: 
  • Received for publication February 5, 2019
  • Accepted for publication May 2, 2019
  • .

Author Information

  1. Patrick T. O’Kane1,2,*,
  2. Quentin M. Dudley1,3,*,
  3. Aislinn K. McMillan1,2,
  4. Michael C. Jewett1,3,4, and
  5. Milan Mrksich1,2,4,
  1. 1Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.
  2. 2Department of Chemistry, Northwestern University, Evanston, IL, USA.
  3. 3Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.
  4. 4Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
  1. Corresponding author. Email: milan.mrksich{at}northwestern.edu (M.M.); m-jewett{at}northwestern.edu (M.C.J.)
  • * These authors contributed equally to this work.

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