Research ArticleCELL BIOLOGY

Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7

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Science Advances  31 Jul 2019:
Vol. 5, no. 7, eaau9433
DOI: 10.1126/sciadv.aau9433

Article Information

vol. 5 no. 7

Online ISSN: 
History: 
  • Received for publication July 30, 2018
  • Accepted for publication June 26, 2019
  • .

Author Information

  1. Scott McComb1,*,
  2. Pik Ki Chan1,*,
  3. Anna Guinot1,*,
  4. Holmfridur Hartmannsdottir1,
  5. Silvia Jenni1,
  6. Maria Pamela Dobay1,2,
  7. Jean-Pierre Bourquin1 and
  8. Beat C. Bornhauser1,
  1. 1Department of Oncology and Children’s Research Centre, University Children’s Hospital Zürich, 8032 Zürich, Switzerland.
  2. 2IQVIA Technology and Services AG Theaterstrasse 4, 4051 Basel, Switzerland.
  1. Corresponding author. Email: beat.bornhauser{at}kispi.uzh.ch
  • * These authors contributed equally to this work.

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