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Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML

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Science Advances  10 Jul 2019:
Vol. 5, no. 7, eaaw4304
DOI: 10.1126/sciadv.aaw4304

Article Information

vol. 5 no. 7

Online ISSN: 
  • Received for publication December 19, 2018
  • Accepted for publication May 31, 2019
  • .

Author Information

  1. Janus S. Jakobsen1,2,3,*,,
  2. Linea G. Laursen1,2,3,,
  3. Mikkel B. Schuster1,2,3,,
  4. Sachin Pundhir1,2,3,4,
  5. Erwin Schoof1,2,3,
  6. Ying Ge1,2,3,
  7. Teresa d’Altri1,2,3,
  8. Kristoffer Vitting-Seerup4,
  9. Nicolas Rapin1,2,3,4,,
  10. Coline Gentil1,2,3,
  11. Johan Jendholm1,2,3,
  12. Kim Theilgaard-Mönch1,2,3,5,
  13. Kristian Reckzeh1,2,3,
  14. Lars Bullinger6,
  15. Konstanze Döhner7,
  16. Peter Hokland8,
  17. Jude Fitzgibbon9 and
  18. Bo T. Porse1,2,3,§
  1. 1The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  2. 2Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.
  3. 3Danish Stem Cell Centre (DanStem) Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  4. 4The Bioinformatics Centre, Department of Biology, Faculty of Natural Sciences, University of Copenhagen, Copenhagen, Denmark.
  5. 5Department of Hematology, Rigshospitalet, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark.
  6. 6Department of Hematology, Oncology, and Tumor Immunology, Charité University Medicine, Berlin, Germany.
  7. 7Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
  8. 8Department of Hematology, Aarhus University Hospital, Aarhus, Denmark.
  9. 9Centre for Haemato-Oncology, Queen Mary University of London, London, UK.
  1. §Corresponding author. Email: bo.porse{at}
  • * Present address: Symphogen A/S, Ballerup, Denmark.

  • These authors contributed equally to this work.

  • Present address: Deloitte Consulting, Copenhagen, Denmark.


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