Research ArticleCELL BIOLOGY

Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional area

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Science Advances  24 Jul 2019:
Vol. 5, no. 7, eaaw7243
DOI: 10.1126/sciadv.aaw7243

Article Information

vol. 5 no. 7

Online ISSN: 
History: 
  • Received for publication January 18, 2019
  • Accepted for publication June 19, 2019
  • .

Author Information

  1. Runchen Zhao1,2,*,
  2. Alexandros Afthinos1,2,*,
  3. Tian Zhu1,2,
  4. Panagiotis Mistriotis1,2,
  5. Yizeng Li2,3,
  6. Selma A. Serra4,
  7. Yuqi Zhang1,2,
  8. Christopher L. Yankaskas1,2,
  9. Shuyu He1,
  10. Miguel A. Valverde4,
  11. Sean X. Sun1,2,3,5,6 and
  12. Konstantinos Konstantopoulos1,2,5,6,7,
  1. 1Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  2. 2Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.
  3. 3Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  4. 4Laboratory of Molecular Physiology, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain.
  5. 5Johns Hopkins Physical Sciences-Oncology Center, Johns Hopkins University, Baltimore, MD 21218, USA.
  6. 6Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  7. 7Department of Oncology, Johns Hopkins University, Baltimore, MD 21205, USA.
  1. Corresponding author. Email: konstant{at}jhu.edu
  • * These authors contributed equally to this work.

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