Research ArticleRESEARCH METHODS

High-speed AFM reveals accelerated binding of agitoxin-2 to a K+ channel by induced fit

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Science Advances  03 Jul 2019:
Vol. 5, no. 7, eaax0495
DOI: 10.1126/sciadv.aax0495

Article Information

vol. 5 no. 7

Online ISSN: 
History: 
  • Received for publication February 17, 2019
  • Accepted for publication May 23, 2019
  • .

Author Information

  1. A. Sumino1,2,3,4,*,,
  2. T. Sumikama1,4,*,
  3. T. Uchihashi5,6, and
  4. S. Oiki4,,
  1. 1Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kanazawa 920-1192, Japan.
  2. 2Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan.
  3. 3PRESTO, Japan Science and Technology Agency (JST), Saitama 332-0012, Japan.
  4. 4Department of Molecular Physiology and Biophysics, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
  5. 5Department of Physics and Structural Biology Research Center, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan.
  6. 6Exploratory Research Center on Life and Living Systems, National Institute of Natural Sciences, 5-1 Higashiyama, Myodaiji, Okazaki, Aichi 444-8787, Japan.
  1. Corresponding author. Email: sumino{at}staff.kanazawa-u.ac.jp (A.S.); uchihast{at}d.phys.nagoya-u.ac.jp (T.U.); oiki-fki{at}umin.ac.jp (S.O.)
  • * These authors contributed equally to this work.

  • Present address: Biomedical Imaging Research Center, University of Fukui, Fukui 910-1193, Japan.

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