Research ArticleCELL BIOLOGY

Osteoblastic lysosome plays a central role in mineralization

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Science Advances  03 Jul 2019:
Vol. 5, no. 7, eaax0672
DOI: 10.1126/sciadv.aax0672

Article Information

vol. 5 no. 7

Online ISSN: 
History: 
  • Received for publication February 19, 2019
  • Accepted for publication May 28, 2019
  • .

Author Information

  1. Tomoaki Iwayama1,*,
  2. Tomoko Okada2,*,
  3. Tsugumi Ueda1,
  4. Kiwako Tomita1,
  5. Shuji Matsumoto1,
  6. Masahide Takedachi1,
  7. Satoshi Wakisaka3,
  8. Takeshi Noda4,
  9. Taku Ogura5,
  10. Tomomichi Okano5,
  11. Peter Fratzl6,
  12. Toshihiko Ogura2, and
  13. Shinya Murakami1,
  1. 1Department of Periodontology, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan.
  2. 2Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8566, Japan.
  3. 3Department of Oral Anatomy and Development, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan.
  4. 4Center for Frontier Oral Science, Graduate School of Dentistry, and Graduate School of Frontier BioSciences, Osaka University, Osaka 565-0871, Japan.
  5. 5Lion Corporation, Tokyo 132-0035, Japan.
  6. 6Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, Potsdam-Golm 14476, Germany.
  1. Corresponding author. Email: t-ogura{at}aist.go.jp (To. Ogura); ipshinya{at}dent.osaka-u.ac.jp (S. Mu.)
  • * These authors contributed equally to this work.

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