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CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism

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Science Advances  03 Jul 2019:
Vol. 5, no. 7, eaax2887
DOI: 10.1126/sciadv.aax2887

Article Information

vol. 5 no. 7

Online ISSN: 
History: 
  • Received for publication March 10, 2019
  • Accepted for publication May 28, 2019
  • .

Author Information

  1. Andrea Piunti1,2,
  2. Edwin R. Smith1,2,
  3. Marc A. J. Morgan1,2,
  4. Michal Ugarenko1,2,
  5. Natalia Khaltyan3,
  6. Kathryn A. Helmin4,
  7. Caila A. Ryan1,2,
  8. David C. Murray2,
  9. Ryan A. Rickels1,2,
  10. Bahar D. Yilmaz5,
  11. Emily J. Rendleman1,2,
  12. Jeffrey N. Savas3,
  13. Benjamin D. Singer1,2,4,
  14. Serdar E. Bulun5 and
  15. Ali Shilatifard1,2,*
  1. 1Simpson Querrey Center for Epigenetics, Northwestern University Feinberg School of Medicine, 320 East Superior Street, Chicago, IL 60611, USA.
  2. 2Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, 320 East Superior Street, Chicago, IL 60611, USA.
  3. 3Department of Neurology, Northwestern University Feinberg School of Medicine, 320 East Superior Street, Chicago, IL 60611, USA.
  4. 4Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, 320 East Superior Street, Chicago, IL 60611, USA.
  5. 5Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, 320 East Superior Street, Chicago, IL 60611, USA.
  1. *Corresponding author. Email: ash{at}northwestern.edu

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