Research ArticleCELL BIOLOGY
Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD
- Jason Karch1,2,*,†,
- Michael J. Bround1,*,
- Hadi Khalil1,
- Michelle A. Sargent1,
- Nadina Latchman3,
- Naohiro Terada4,
- Pablo M. Peixoto3 and
- Jeffery D. Molkentin1,5,†
- 1Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH, USA.
- 2Department of Molecular Physiology and Biophysics, Cardiovascular Research Institute, Baylor College of Medicine, Houston TX, USA.
- 3Baruch College and Graduate Center of City University of New York, NY, USA.
- 4Department of Pathology, University of Florida College of Medicine, Gainesville, FL, USA.
- 5Howard Hughes Medical Institute, Chevy Chase, MD, USA.
- ↵†Corresponding author. Email: jeff.molkentin{at}cchmc.org (J.D.M.); jason.karch{at}bcm.edu (J.K.)
↵* These authors contributed equally to this work.
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Science Advances 28 Aug 2019:
Vol. 5, no. 8, eaaw4597
DOI: 10.1126/sciadv.aaw4597
Vol. 5, no. 8, eaaw4597
DOI: 10.1126/sciadv.aaw4597
Jason Karch
Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH, USA.Department of Molecular Physiology and Biophysics, Cardiovascular Research Institute, Baylor College of Medicine, Houston TX, USA.
Michael J. Bround
Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH, USA.
Hadi Khalil
Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH, USA.
Michelle A. Sargent
Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH, USA.
Nadina Latchman
Baruch College and Graduate Center of City University of New York, NY, USA.
Naohiro Terada
Department of Pathology, University of Florida College of Medicine, Gainesville, FL, USA.
Pablo M. Peixoto
Baruch College and Graduate Center of City University of New York, NY, USA.
Jeffery D. Molkentin
Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH, USA.Howard Hughes Medical Institute, Chevy Chase, MD, USA.