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Cell cycle progression in confining microenvironments is regulated by a growth-responsive TRPV4-PI3K/Akt-p27Kip1 signaling axis

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Science Advances  07 Aug 2019:
Vol. 5, no. 8, eaaw6171
DOI: 10.1126/sciadv.aaw6171

Article Information

vol. 5 no. 8

Online ISSN: 
History: 
  • Received for publication January 9, 2019
  • Accepted for publication June 28, 2019
  • .

Author Information

  1. Sungmin Nam1,
  2. Vivek Kumar Gupta1,
  3. Hong-pyo Lee1,
  4. Joanna Y. Lee1,*,
  5. Katrina M. Wisdom1,,
  6. Sushama Varma2,
  7. Eliott Marie Flaum3,
  8. Ciara Davis4,
  9. Robert B. West2 and
  10. Ovijit Chaudhuri1,
  1. 1Department of Mechanical Engineering, Stanford University, CA, USA.
  2. 2Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  3. 3Biophysics Program, Stanford University, CA, USA.
  4. 4Department of Biomedical Engineering, University of Michigan, MI, USA.
  1. Corresponding author. Email: chaudhuri{at}stanford.edu
  • * Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA 94080, USA.

  • Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.

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