Research ArticleMICROBIOLOGY

Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis

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Science Advances  28 Aug 2019:
Vol. 5, no. 8, eaaw7696
DOI: 10.1126/sciadv.aaw7696

Article Information

vol. 5 no. 8

Online ISSN: 
History: 
  • Received for publication January 24, 2019
  • Accepted for publication July 18, 2019
  • .

Author Information

  1. Mikiyasu Sakanaka1,*,,
  2. Morten Ejby Hansen2,*,
  3. Aina Gotoh3,
  4. Toshihiko Katoh3,
  5. Keisuke Yoshida4,
  6. Toshitaka Odamaki4,
  7. Hiroyuki Yachi1,
  8. Yuta Sugiyama1,
  9. Shin Kurihara1,,
  10. Junko Hirose5,
  11. Tadasu Urashima6,
  12. Jin-zhong Xiao4,
  13. Motomitsu Kitaoka7,
  14. Satoru Fukiya8,
  15. Atsushi Yokota8,
  16. Leila Lo Leggio9,
  17. Maher Abou Hachem2,§ and
  18. Takane Katayama1,3,§
  1. 1Faculty of Bioresources and Environmental Sciences, Ishikawa Prefectural University, Nonoichi, Ishikawa 921-8836, Japan.
  2. 2Department of Biotechnology and Bioengineering, Technical University of Denmark, Søltofts Plads, DK-2800 Kgs. Lyngby, Denmark.
  3. 3Graduate School of Biostudies, Kyoto University, Kyoto 606-8502, Japan.
  4. 4Next Generation Science Institute, Morinaga Milk Industry Co. Ltd., Zama, Kanagawa 252-8583, Japan.
  5. 5School of Human Cultures, The University of Shiga Prefecture, Hikone, Shiga 522-8533, Japan.
  6. 6Department of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
  7. 7Food Research Institute, National Agriculture and Food Research Organization, Tsukuba, Ibaraki 305-8642, Japan.
  8. 8Research Faculty of Agriculture, Hokkaido University, Sapporo, Hokkaido 060-8589, Japan.
  9. 9Department of Chemistry, University of Copenhagen, Copenhagen 2100, Denmark.
  1. §Corresponding author. Email: takane{at}lif.kyoto-u.ac.jp (T.K.); maha{at}bio.dtu.dk (M.A.H.)
  • * These authors contributed equally to this work.

  • Present address: National Food Institute, Technical University of Denmark, Kemitorvet, DK-2800 Kgs. Lyngby, Denmark.

  • Present address: Faculty of Biology-Oriented Science and Technology, Kindai University, Kinokawa, Wakayama 649-6493, Japan.

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