Research ArticleIMMUNOLOGY

Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes

See allHide authors and affiliations

Science Advances  21 Aug 2019:
Vol. 5, no. 8, eaaw8330
DOI: 10.1126/sciadv.aaw8330

Article Information

vol. 5 no. 8

Online ISSN: 
History: 
  • Received for publication January 30, 2019
  • Accepted for publication July 12, 2019
  • .

Author Information

  1. Yehezqel Elyahu1,2,3,*,
  2. Idan Hekselman3,4,*,
  3. Inbal Eizenberg-Magar5,
  4. Omer Berner1,2,3,
  5. Itai Strominger1,2,3,
  6. Maya Schiller6,
  7. Kritika Mittal1,2,3,
  8. Anna Nemirovsky1,2,3,
  9. Ekaterina Eremenko1,2,3,
  10. Assaf Vital3,4,
  11. Eyal Simonovsky3,4,
  12. Vered Chalifa-Caspi3,
  13. Nir Friedman5,
  14. Esti Yeger-Lotem3,4, and
  15. Alon Monsonego1,2,3,
  1. 1The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
  2. 2Zlotowski Neuroscience Center and Regenerative Medicine and Stem Cell Research Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
  3. 3National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
  4. 4Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
  5. 5Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel.
  6. 6Departments of Immunology and Neuroscience, Rappaport Faculty of Medicine, and the Integrated Cancer Center, Technion-Israel Institute of Technology, Haifa 3525422, Israel.
  1. Corresponding author. Email: alonmon{at}bgu.ac.il (A.M.); estiyl{at}bgu.ac.il (E.Y.-L.)
  • * These authors contributed equally to this work.

Altmetric

Article usage

Article usage: August 2019 to October 2020

AbstractFullPdf
Aug 20191744382946
Sep 2019621872365
Oct 201927618214
Nov 201917544265
Dec 201921747272
Jan 20209563215
Feb 202016605193
Mar 202030514213
Apr 202021516272
May 2020174922194
Jun 202041381174
Jul 202029317156
Aug 202031319186
Sep 202043373208
Oct 202056394181

Stay Connected to Science Advances

Navigate This Article