Research ArticleHEALTH AND MEDICINE

The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia

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Science Advances  04 Sep 2019:
Vol. 5, no. 9, eaaw0109
DOI: 10.1126/sciadv.aaw0109

Article Information

vol. 5 no. 9

Online ISSN: 
History: 
  • Received for publication November 9, 2018
  • Accepted for publication August 6, 2019
  • .

Author Information

  1. John Muthii Muriuki1,*,
  2. Alexander J. Mentzer2,*,,
  3. Gavin Band2,
  4. James J. Gilchrist2,3,
  5. Tommy Carstensen4,
  6. Swaib A. Lule5,6,
  7. Morgan M. Goheen7,8,
  8. Fatou Joof7,
  9. Wandia Kimita1,
  10. Reagan Mogire1,
  11. Clare L. Cutland9,
  12. Amidou Diarra10,
  13. Anna Rautanen2,
  14. Cristina Pomilla4,
  15. Deepti Gurdasani4,
  16. Kirk Rockett2,
  17. Neema Mturi1,
  18. Francis M. Ndungu1,
  19. J. Anthony G. Scott1,6,
  20. Sodiomon B. Sirima10,
  21. Alireza Morovat11,
  22. Andrew M. Prentice7,
  23. Shabir A. Madhi9,
  24. Emily L. Webb6,
  25. Alison M. Elliott5,6,
  26. Philip Bejon1,12,
  27. Manjinder S. Sandhu4,
  28. Adrian V. S. Hill2,13,
  29. Dominic P. Kwiatkowski2,4,
  30. Thomas N. Williams1,12,14,
  31. Carla Cerami7 and
  32. Sarah H. Atkinson1,3,12,
  1. 1Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Programme, Kilifi, Kenya.
  2. 2Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  3. 3Department of Paediatrics, University of Oxford, Oxford, UK.
  4. 4Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  5. 5Medical Research Council/Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
  6. 6London School of Hygiene and Tropical Medicine, London, UK.
  7. 7Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.
  8. 8University of North Carolina School of Medicine, CB 7435, Chapel Hill, North Carolina USA.
  9. 9Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
  10. 10Centre de Recherche Action en Sante (GRAS), 06 BP 10248, Ouagadougou 06, Burkina Faso.
  11. 11Department of Clinical Biochemistry, Oxford University Hospitals, Oxford, UK.
  12. 12Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  13. 13Centre for Clinical Vaccinology and Tropical Medicine and the Jenner Institute Laboratories, University of Oxford, Oxford, UK.
  14. 14Department of Medicine, Imperial College, London, UK.
  1. Corresponding author. Email: alexander.mentzer{at}ndm.ox.ac.uk (A.J.M.); satkinson{at}kemri-wellcome.org (S.H.A.)
  • * These authors contributed equally to this work.

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