Research ArticleHEALTH AND MEDICINE

The essential role of the transporter ABCG2 in the pathophysiology of erythropoietic protoporphyria

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Science Advances  18 Sep 2019:
Vol. 5, no. 9, eaaw6127
DOI: 10.1126/sciadv.aaw6127

Article Information

vol. 5 no. 9

Online ISSN: 
History: 
  • Received for publication January 9, 2019
  • Accepted for publication August 23, 2019
  • .

Author Information

  1. Pengcheng Wang1,*,
  2. Madhav Sachar1,*,
  3. Jie Lu1,
  4. Amina I. Shehu1,
  5. Junjie Zhu1,
  6. Jing Chen1,
  7. Ke Liu1,
  8. Karl E. Anderson2,
  9. Wen Xie1,
  10. Frank J. Gonzalez3,
  11. Curtis D. Klaassen4 and
  12. Xiaochao Ma1,
  1. 1Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  2. 2Porphyria Laboratory and Center, Departments of Preventive Medicine and Community Health, and Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
  3. 3Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  4. 4Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  1. Corresponding author. Email: mxiaocha{at}pitt.edu
  • * These authors contributed equally to this work.

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