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Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer

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Science Advances  18 Sep 2019:
Vol. 5, no. 9, eaax2277
DOI: 10.1126/sciadv.aax2277

Article Information

vol. 5 no. 9

Online ISSN: 
History: 
  • Received for publication March 8, 2019
  • Accepted for publication August 19, 2019
  • .

Author Information

  1. Lei Wang1,2,
  2. Lixiao Zhang1,2,
  3. Li Li1,2,
  4. Jingsheng Jiang1,2,
  5. Zhen Zheng3,
  6. Jialin Shang3,
  7. Chengxiang Wang3,
  8. Weilin Chen1,2,
  9. Qichao Bao1,2,
  10. Xiaoli Xu1,2,
  11. Zhengyu Jiang1,2,*,
  12. Jian Zhang3,4,* and
  13. Qidong You1,2,*
  1. 1State Key Laboratory of Natural Medicines and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  2. 2Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  3. 3Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Medicinal Bioinformatics Center, Shanghai Jiao-Tong University School of Medicine (SJTU-SM), Shanghai, 200025, China.
  4. 4School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
  1. *Corresponding author. Email: jiangzhengyucpu{at}163.com (Z.J.); jian.zhang{at}sjtu.edu.cn (J.Z.); youqd{at}163.com (Q.Y.)

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