Research ArticleMOLECULAR BIOLOGY
Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight
- View ORCID ProfileSeung-Ah Lee1,*,†,
- View ORCID ProfileKryscilla Jian Zhang Yang1,*,
- View ORCID ProfilePierre-Jacques Brun1,*,
- View ORCID ProfileJosie A. Silvaroli2,
- Jason J. Yuen1,
- View ORCID ProfileIgor Shmarakov1,
- Hongfeng Jiang1,
- Jun B. Feranil1,
- View ORCID ProfileXueting Li3,
- View ORCID ProfileAtreju I. Lackey4,
- View ORCID ProfileWojciech Krężel5,
- View ORCID ProfileRudolph L. Leibel6,
- View ORCID ProfileJenny Libien7,
- View ORCID ProfileJudith Storch4,
- Marcin Golczak2,8 and
- View ORCID ProfileWilliam S. Blaner1,*,‡
- 1Department of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
- 2Department of Pharmacology, Case Western Reserve University, Cleveland, OH, USA.
- 3PhD Program in Nutritional and Metabolic Biology, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
- 4Department of Nutritional Sciences and Rutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ, USA.
- 5Institut de Génétique et de Biologie Moléculaire et Cellulaire, U1258, CNRS, UMR 7104, Unistra, Illkirch 67404, France.
- 6Department of Pediatrics, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
- 7Department of Pathology, SUNY Downstate Medical Center, Brooklyn, NY, USA.
- 8Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, OH, USA.
- ↵‡Corresponding author. Email: wsb2{at}cumc.columbia.edu
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Science Advances 11 Mar 2020:
Vol. 6, no. 11, eaay8937
DOI: 10.1126/sciadv.aay8937
Vol. 6, no. 11, eaay8937
DOI: 10.1126/sciadv.aay8937
Seung-Ah Lee
1Department of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Kryscilla Jian Zhang Yang
1Department of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Pierre-Jacques Brun
1Department of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Josie A. Silvaroli
2Department of Pharmacology, Case Western Reserve University, Cleveland, OH, USA.
Jason J. Yuen
1Department of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Igor Shmarakov
1Department of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Hongfeng Jiang
1Department of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Jun B. Feranil
1Department of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Xueting Li
3PhD Program in Nutritional and Metabolic Biology, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Atreju I. Lackey
4Department of Nutritional Sciences and Rutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ, USA.
Wojciech Krężel
5Institut de Génétique et de Biologie Moléculaire et Cellulaire, U1258, CNRS, UMR 7104, Unistra, Illkirch 67404, France.
Rudolph L. Leibel
6Department of Pediatrics, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Jenny Libien
7Department of Pathology, SUNY Downstate Medical Center, Brooklyn, NY, USA.
Judith Storch
4Department of Nutritional Sciences and Rutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ, USA.
Marcin Golczak
2Department of Pharmacology, Case Western Reserve University, Cleveland, OH, USA.
8Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, OH, USA.
William S. Blaner
1Department of Medicine, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, NY, USA.