Research ArticleCELL BIOLOGY
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes
- View ORCID ProfilePatrick Han1,*,
- View ORCID ProfileDouglas Hanlon2,*,
- View ORCID ProfileNajla Arshad3,
- Jung Seok Lee4,
- Kazuki Tatsuno2,
- Eve Robinson2,
- Renata Filler2,
- Olga Sobolev2,
- Christine Cote5,
- Felix Rivera-Molina6,
- Derek Toomre6,
- View ORCID ProfileTarek Fahmy1,2,3,4,† and
- View ORCID ProfileRichard Edelson2,†
- 1Department of Chemical and Environmental Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.
- 2Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
- 3Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06511, USA.
- 4Department of Biomedical Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.
- 5Yale Flow Cytometry Facility, School of Medicine, Yale University, New Haven, CT 06511, USA.
- 6Yale CINEMA Lab, School of Medicine, Yale University, New Haven, CT 06511, USA.
- ↵†Corresponding author. Email: tarek.fahmy{at}yale.edu (T.F.); redelson{at}yale.edu (R.E.)
↵* These authors contributed equally to this work.
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Science Advances 11 Mar 2020:
Vol. 6, no. 11, eaaz1580
DOI: 10.1126/sciadv.aaz1580
Vol. 6, no. 11, eaaz1580
DOI: 10.1126/sciadv.aaz1580
Patrick Han
1Department of Chemical and Environmental Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.
Douglas Hanlon
2Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Najla Arshad
3Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Jung Seok Lee
4Department of Biomedical Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.
Kazuki Tatsuno
2Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Eve Robinson
2Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Renata Filler
2Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Olga Sobolev
2Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Christine Cote
5Yale Flow Cytometry Facility, School of Medicine, Yale University, New Haven, CT 06511, USA.
Felix Rivera-Molina
6Yale CINEMA Lab, School of Medicine, Yale University, New Haven, CT 06511, USA.
Derek Toomre
6Yale CINEMA Lab, School of Medicine, Yale University, New Haven, CT 06511, USA.
Tarek Fahmy
1Department of Chemical and Environmental Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.
2Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
3Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06511, USA.
4Department of Biomedical Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.
Richard Edelson
2Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
