Lineage hierarchies and stochasticity ensure the long-term maintenance of adult neural stem cells

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Science Advances  29 Apr 2020:
Vol. 6, no. 18, eaaz5424
DOI: 10.1126/sciadv.aaz5424

Article Information

vol. 6 no. 18

Online ISSN: 
  • Received for publication September 18, 2019
  • Accepted for publication February 11, 2020
  • .

Author Information

  1. Emmanuel Than-Trong1,2,
  2. Bahareh Kiani3,
  3. Nicolas Dray1,
  4. Sara Ortica1,
  5. Benjamin Simons4,5,6,
  6. Steffen Rulands3,7,
  7. Alessandro Alunni1,*, and
  8. Laure Bally-Cuif1,*,
  1. 1Zebrafish Neurogenetics Unit, Institut Pasteur, UMR3738, CNRS, Team supported by the Ligue Nationale Contre le Cancer, Paris 75015, France.
  2. 2Université Paris-Saclay, Ecole Doctorale Biosigne, Le Kremlin-Bicêtre, France.
  3. 3Max Planck Institute for the Physics of Complex Systems, Nöthnitzer Straße 38, 01187 Dresden, Germany.
  4. 4Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, UK.
  5. 5Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge UK.
  6. 6Wellcome Trust/Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge UK.
  7. 7Center for Systems Biology Dresden, Pfotenhauer Str. 108, 01307 Dresden, Germany.
  1. *Corresponding author. Email: laure.bally-cuif{at} (L.B.-C.); alessandro.alunni{at} (A.A.)
  • These authors contributed equally to this work.


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