Research ArticleLIFE SCIENCES

Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment

See allHide authors and affiliations

Science Advances  29 Apr 2020:
Vol. 6, no. 18, eaaz8031
DOI: 10.1126/sciadv.aaz8031

Article Information

vol. 6 no. 18

Online ISSN: 
History: 
  • Received for publication October 10, 2019
  • Accepted for publication February 4, 2020
  • .

Author Information

  1. Leiming Wang1,
  2. Chiang-Min Cheng1,
  3. Jun Qin2,
  4. Mafei Xu1,
  5. Chung-Yang Kao1,
  6. Jingjing Shi3,
  7. Erli You3,
  8. Wanchun Gong3,
  9. Laura Pedro Rosa4,
  10. Peter Chase4,
  11. Louis Scampavia4,
  12. Franck Madoux4,*,
  13. Timothy Spicer4,
  14. Peter Hodder4,*,
  15. H. Eric Xu3,
  16. Sophia Y. Tsai1,5, and
  17. Ming-Jer Tsai1,5,
  1. 1Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  2. 2CAS Key Laboratory of Tissue Microenvironment and Tumor, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
  3. 3CAS Key Laboratory of Receptor Research, VARI-SIMM Center, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  4. 4Scripps Research, Molecular Screening Center, Jupiter, FL 33458, USA.
  5. 5Department of Medicine and Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  1. Corresponding author. Email: stsai{at}bcm.edu (S.Y.T.); mtsai{at}bcm.edu (M.-J.T.)
  • * Present address: Discovery Technologies, One Amgen Center Drive 29-1-B, Thousand Oaks, CA 91320, USA.

Altmetric

Article usage

Article usage: April 2020 to September 2020

AbstractFullPdf
Apr 2020142939172
May 20201631526434
Jun 20208288120
Jul 2020130474
Aug 2020525269
Sep 2020518051

Stay Connected to Science Advances

Navigate This Article