Exosome-templated nanoplasmonics for multiparametric molecular profiling

Xingjie Wu; Haitao Zhao; Auginia Natalia; Carine Z. J. Lim; Nicholas R. Y. Ho; Chin-Ann J. Ong; Melissa C. C. Teo; Jimmy B. Y. So; Huilin Shao

doi:10.1126/sciadv.aba2556

Research ArticleBIOPHYSICS

Exosome-templated nanoplasmonics for multiparametric molecular profiling

View ORCID ProfileXingjie Wu¹,*,
View ORCID ProfileHaitao Zhao¹,*,
View ORCID ProfileAuginia Natalia¹,²,
Carine Z. J. Lim¹,²,
View ORCID ProfileNicholas R. Y. Ho¹,³,
View ORCID ProfileChin-Ann J. Ong⁴,
Melissa C. C. Teo⁴,
Jimmy B. Y. So⁵,⁶ and
View ORCID ProfileHuilin Shao ¹,²,³,⁵,†

¹Institute for Health Innovation and Technology, National University of Singapore, Singapore 117599, Singapore.
²Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore 117583, Singapore.
³Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.
⁴Division of Surgical Oncology, National Cancer Centre, Singapore 169610, Singapore.
⁵Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
⁶Division of Surgical Oncology, National University Cancer Institute, Singapore 169610, Singapore.

↵†Corresponding author. Email: huilin.shao{at}nus.edu.sg

↵* These authors contributed equally to this work.

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Science Advances 06 May 2020:
Vol. 6, no. 19, eaba2556
DOI: 10.1126/sciadv.aba2556

Xingjie Wu

1Institute for Health Innovation and Technology, National University of Singapore, Singapore 117599, Singapore.

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Haitao Zhao

1Institute for Health Innovation and Technology, National University of Singapore, Singapore 117599, Singapore.

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Auginia Natalia

1Institute for Health Innovation and Technology, National University of Singapore, Singapore 117599, Singapore.

2Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore 117583, Singapore.

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ORCID record for Auginia Natalia

Carine Z. J. Lim

1Institute for Health Innovation and Technology, National University of Singapore, Singapore 117599, Singapore.

2Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore 117583, Singapore.

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Nicholas R. Y. Ho

1Institute for Health Innovation and Technology, National University of Singapore, Singapore 117599, Singapore.

3Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.

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Chin-Ann J. Ong

4Division of Surgical Oncology, National Cancer Centre, Singapore 169610, Singapore.

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Melissa C. C. Teo

4Division of Surgical Oncology, National Cancer Centre, Singapore 169610, Singapore.

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Jimmy B. Y. So

5Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.

6Division of Surgical Oncology, National University Cancer Institute, Singapore 169610, Singapore.

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Huilin Shao

1Institute for Health Innovation and Technology, National University of Singapore, Singapore 117599, Singapore.

2Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore 117583, Singapore.

3Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138673, Singapore.

5Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.

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For correspondence: huilin.shao@nus.edu.sg

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