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Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation

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Science Advances  08 Jan 2020:
Vol. 6, no. 2, eaax5936
DOI: 10.1126/sciadv.aax5936

Article Information

vol. 6 no. 2

Online ISSN: 
History: 
  • Received for publication April 5, 2019
  • Accepted for publication November 8, 2019
  • .

Author Information

  1. Kirsten S. Evonuk1,
  2. Ryan E. Doyle1,
  3. Carson E. Moseley2,3,
  4. Ian M. Thornell4,*,
  5. Keith Adler1,
  6. Amanda M. Bingaman1,
  7. Mark O. Bevensee4,
  8. Casey T. Weaver2,
  9. Booki Min5 and
  10. Tara M. DeSilva1,
  1. 1Department of Neurosciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
  2. 2Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
  3. 3University of California, San Francisco, CA, USA.
  4. 4Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA.
  5. 5Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
  1. Corresponding author. Email: desilvt{at}ccf.org
  • * Present address: University of Iowa, Iowa, IA, USA.

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