The obesity-induced adipokine sST2 exacerbates adipose Treg and ILC2 depletion and promotes insulin resistance

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Science Advances  13 May 2020:
Vol. 6, no. 20, eaay6191
DOI: 10.1126/sciadv.aay6191

Article Information

vol. 6 no. 20

Online ISSN: 
  • Received for publication July 4, 2019
  • Accepted for publication March 2, 2020
  • .

Author Information

  1. Xu-Yun Zhao1,2,3,*,
  2. Linkang Zhou1,
  3. Zhimin Chen1,
  4. Yewei Ji4,
  5. Xiaoling Peng1,
  6. Ling Qi4,
  7. Siming Li1 and
  8. Jiandie D. Lin1,*
  1. 1Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.
  2. 2Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Key Laboratory of Cell Differentiation and Apoptosis of National Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  3. 3Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
  4. 4Department of Molecular and Integrative Physiology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.
  1. *Corresponding author. Email: jdlin{at} (J.D.L.); xuyunzhao{at} (X.-Y.Z.)


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