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Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer’s disease detected by dynamic glucose-enhanced MRI

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Science Advances  13 May 2020:
Vol. 6, no. 20, eaba3884
DOI: 10.1126/sciadv.aba3884

Article Information

vol. 6 no. 20

Online ISSN: 
History: 
  • Received for publication November 29, 2019
  • Accepted for publication February 27, 2020
  • .

Author Information

  1. Jianpan Huang1,
  2. Peter C. M. van Zijl2,3,
  3. Xiongqi Han1,
  4. Celia M. Dong4,
  5. Gerald W. Y. Cheng5,
  6. Kai-Hei Tse5,
  7. Linda Knutsson2,6,
  8. Lin Chen2,3,
  9. Joseph H. C. Lai1,
  10. Ed X. Wu4,
  11. Jiadi Xu2,3,* and
  12. Kannie W. Y. Chan1,2,7,*
  1. 1Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, China.
  2. 2Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  3. 3F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, MD, USA.
  4. 4Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong, China.
  5. 5Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
  6. 6Department of Medical Radiation Physics, Lund University, Lund, Sweden.
  7. 7City University of Hong Kong Shenzhen Research Institute, Shenzhen, China.
  1. *Corresponding author. Email: kanniew.y.c{at}cityu.edu.hk (K.W.Y.C.); xuj{at}kennedykrieger.org (J.X.)

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