Research ArticleVIROLOGY

Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor

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Science Advances  13 May 2020:
Vol. 6, no. 20, eaba5147
DOI: 10.1126/sciadv.aba5147

Article Information

vol. 6 no. 20

Online ISSN: 
History: 
  • Received for publication December 10, 2019
  • Accepted for publication February 28, 2020
  • .

Author Information

  1. Dan Yue1,
  2. Zhujun Chen1,
  3. Fanli Yang1,
  4. Fei Ye1,
  5. Sheng Lin1,
  6. Bin He1,
  7. Yanwei Cheng1,2,
  8. Jichao Wang1,
  9. Zimin Chen1,
  10. Xi Lin1,
  11. Jing Yang1,
  12. Hua Chen1,
  13. Zhonglin Zhang1,
  14. Yu You1,
  15. Honglu Sun1,
  16. Ao Wen1,
  17. Lingling Wang1,
  18. Yue Zheng1,
  19. Yu Cao1,3,
  20. Yuhua Li1,4,* and
  21. Guangwen Lu1,*
  1. 1West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan 610041, China.
  2. 2Department of Emergency, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, 450003, China.
  3. 3Disaster Medicine Center, Sichuan University, Chengdu, Sichuan 610041, China.
  4. 4Department of Arbovirus Vaccine, National Institutes for Food and Drug Control, Beijing, 102629, China.
  1. *Corresponding author. Email: liyuhua{at}nifdc.org.cn (Y.L.); lugw{at}scu.edu.cn (G.L.)

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