Research ArticleIMMUNOLOGY

Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation

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Science Advances  20 May 2020:
Vol. 6, no. 21, eaaz6717
DOI: 10.1126/sciadv.aaz6717

Article Information

vol. 6 no. 21

Online ISSN: 
  • Received for publication September 29, 2019
  • Accepted for publication March 9, 2020
  • .

Author Information

  1. Chunmei Ma1,*,
  2. Dongxue Yang1,*,
  3. Bingwei Wang2,*,,
  4. Chunyan Wu1,
  5. Yuqing Wu1,
  6. Sheng Li1,
  7. Xue Liu1,
  8. Kara Lassen3,
  9. Lue Dai4, and
  10. Shuo Yang1,
  1. 1Department of Immunology, Key Laboratory of Immunological Environment and Disease, State Key Laboratory of Reproductive Medicine, Center for Global Health, Nanjing Medical University, Nanjing, China.
  2. 2Department of Pharmacology, Nanjing University of Chinese Medicine, Nanjing, China.
  3. 3Roche Innovation Center Basel, Basel, Switzerland.
  4. 4Roche Innovation Center Shanghai, Shanghai, China.
  1. Corresponding author. Email: shuoyang{at} (S.Y.); lue.dai{at} (L.D.); bingweiwang{at} (B.W.)
  • * These authors contributed equally to this work.


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