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Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy

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Science Advances  22 May 2020:
Vol. 6, no. 21, eaaz8521
DOI: 10.1126/sciadv.aaz8521

Article Information

vol. 6 no. 21

Online ISSN: 
  • Received for publication October 14, 2019
  • Accepted for publication March 20, 2020
  • .

Author Information

  1. Stephanie J. Wang1,2,
  2. Ran Li2,
  3. Thomas S. C. Ng2,
  4. Gaurav Luthria2,3,
  5. Madeleine J. Oudin4,
  6. Mark Prytyskach2,
  7. Rainer H. Kohler2,
  8. Ralph Weissleder2,5,6,
  9. Douglas A. Lauffenburger1,* and
  10. Miles A. Miller2,5,*
  1. 1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  2. 2Center for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA, USA.
  3. 3Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  4. 4Department of Biomedical Engineering, Tufts University, Medford, MA, USA.
  5. 5Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  6. 6Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
  1. *Corresponding author. Email: lauffen{at} (D.A.L.); miles.miller{at} (M.A.M.)


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